Wisdom Teeth May Hold Cure for Corneal Blindness

By: Elaine Vittone

ThinkstockPhotos-480050871Corneal blindness affects millions worldwide. To date, the only treatment available is a corneal transplant. But potential new cures are coming from unexpected places—including wisdom teeth!

A husband-and-wife team at the University of Pittsburgh has been working toward the dream of regrowing new corneal tissue for years—that’s Jim Funderburgh, a professor of ophthalmology, and Martha Funderburgh, a research assistant in his lab and a corneal transplant recipient herself.

Working with Sayan Basu, a physician-scientist in Hyderabad, India, and Fatima Syed-Picard, a Pitt postdoc-turned NIH award recipient, the Funderburghs are now developing ways to repair corneal damage—and even prevent corneal scarring from happening in the first place. It turns out that adult stem cells taken from our own eyes and teeth are capable of regenerating this tissue so vital to our focusing power.

Check out the latest Pitt Medcast about this that was inspired by a story from the Spring 2015 issue of Pitt Med magazine.